56:160:506 Materials Chemistry (3) Introduction to the study of materials, including the relationships between the structures and properties of materials.

56:160:508 Organic Mechanisms: Nucleophiles and Bases (3) An introduction to nucleophilic organic reaction mechanisms. How to correctly represent a reaction mechanism. Instruction in critical thinking and problem solving to elucidate and critically evaluate organic reaction mechanisms involving nucleophiles and bases. 
Prerequisite: 50:160:336 or equivalent.

56:160:509 Organic Mechanisms: Electrophiles and Acids (3) An introduction to electrophilic organic reaction mechanisms and what they mean. How to correctly represent a reaction mechanism. Instruction in critical thinking and problem solving to elucidate and critically evaluate organic reaction mechanisms involving electrophiles and acids. Prerequisite: 50:160:336 or equivalent.

56:160:510 Organic Mechanisms: Radicals (3) An introduction to radical organic reaction mechanisms. How to correctly represent single electron movement in a mechanism. Instruction in critical thinking and problem solving to elucidate and critically evaluate radical mechanisms. This course focuses on radical, single electron, and photochemical reactions.  Prerequisite: 50:160:336 or equivalent.

56:160:511 Advanced Organic Chemistry I (3) Advanced survey of organic chemistry. Molecular orbital theory, orbital symmetry correlations, structure and stereochemistry of organic molecules, chemistry of reactive intermediates (including free radicals), photochemistry, structure-reactivity relationships, and molecular rearrangements. Prerequisites: 50:160:335,336, or equivalent.

56:160:512 Advanced Organic Chemistry II (3) Advanced survey of synthetic transformations and reaction mechanisms.

56:160:513 Organic Analysis (3) Interpretation and use of infrared, visible, and ultraviolet spectroscopy; mass spectrometry; and nuclear magnetic resonance for the identification of organic compounds. Combination with separation techniques is included.

56:160:514 Introduction to Molecular Modeling (3) Introduction to the use of computer-assisted molecular modeling techniques for the study of chemical problems; lectures on theoretical principles; instruction in use of modern modeling programs; and computer projects involving solution of chemical problems.

56:160:515 Polymer Chemistry I (3) Introduction to the chemistry of macromolecules, aimed at understanding the relationship between molecular structures and properties of high polymers. This course includes an overview of polymer nomenclature, molecular weight properties, types of polymerization, structure (morphology), characterization, and testing of polymers. Prerequisite: 50:160:336 or equivalent.

56:160:516 Polymer Chemistry II (3) Continuing to explore the chemistry of macromolecules, aimed at understanding the relationship between molecular structures and properties of high polymers. Prerequisite or Co-requisite: 56:160:515.

56:160:517 Polymer Chemistry Laboratory (1) Instruction in the use of major instrumentation for the characterization of physical properties of high polymers.

56:160:519 Fluorocarbons (3) Provides a survey of the chemistry of fluorinated organic molecules emphasizing a broad mechanistic basis. Areas covered include comparisons of fluorinated and hydrocarbon compounds; introduction of organofluorine chemistry; preparation of highly fluorinated molecules; partial and selective fluorination, influence of fluorine and fluorocarbon groups on reaction centers; nucleophilic displacement and elimination from fluorocarbon systems: polyfluoroalkanes, -alkenes, and -alkynes; polyfluoroaromatic compounds; organometallic compounds, and 19F nuclear magnetic resonance.

56:160:520 Math Methods of Chemistry (3) Select aspects of infinite series, vectors and matrices, functions of a complex variable, differential equations, and integral transforms as they are used in chemistry. 

56:160:522 Applied Molecular Spectroscopy (3) Principles of electronic and vibrational spectroscopy of polyatomic molecules. Emphasis on the ways in which spectra yield information about molecular properties.

56:160:523 Statistical Methods of Chemistry (3) Basic statistical thinking and introduction to probability with applications for scientists, with an emphasis on analytical chemistry and biochemistry applications such as forensic science, clinical chemistry and environmental chemistry.

56:160:531 Advanced Inorganic Chemistry (3) An introduction to the discipline of inorganic chemistry including periodic properties, bonding theory, solids, redox, acid/base chemistry, and coordination chemistry.

56:160:532 Organometallic Chemistry (3) Introduction to the chemistry of transition-metal organometallic compounds. Includes an overview of ligand types, reactions, synthesis, and characterization of organometallic compounds.

56:160:533 Symmetry Applications in Chemistry (3) Principles and applications of molecular and crystal symmetry. Topics include point groups, character tables, representations of groups, and other aspects of group theory; symmetry applications in structure and bonding; molecular orbital theory and ligand field theory; and selection rules for electronic, vibrational, and rotational spectroscopy.

56:160:534 NMR Spectroscopy (3) Introduction to the physical principles underlying one of the most widespread and useful tools for chemical analysis. Starting from the descriptions of the phenomenon, a physical picture of NMR experiments in liquids will be developed and the connection between the concepts and actual laboratory practices will be emphasized. The course will include:  roles of chemical shifts, couplings, and relaxation effects in analysis of chemical structure and bonding. Two-dimensional NMR will explain what happens, how the experiment is selected, and how data is interpreted. A survey of solid state NMR and some emerging technologies will be discussed. Prerequisites: 50:160:326 and 346, or equivalent.

56:160:540 Advanced Environmental Chemistry (3) The objective of this course is to develop a solid and practical understanding of the chemistry of air, water, and soil and how anthropogenic activities affect the balance of this chemistry. Specifically, we will examine how chemicals move through the environment, their reaction, and transport phenomena. We would evaluate public policy, student current remediation processes, measurements, and data interpretation. The students should expect to apply chemistry and mathematical concepts to solve remediation process design problems and express and understand scientific models.

56:160:541 Electrochemistry (3) Theory and applications of electrochemical principles and techniques, including voltametry, potentiometry, chronopotentiometry, and spectroelectrochemistry.

56:160:545 Radiochemistry and Radiation Chemistry (3) Interactions of ionizing radiation with matter and the resulting radiation-induced chemical reactions: excitation, ionization, free radical formation and recombination; chemical consequences of nuclear reactions; and “hot atom” chemistry. Prerequisite: 50:160:415 or equivalent.

56:160:547 Computational Chemistry (3) Application of the concepts and techniques of modern computational chemistry to physical organic and biochemistry. Lecture and computer laboratory.

56:160:555 Cheminformatics (3) Application of the concepts and techniques of modern computational chemistry to physical organic and biochemistry. Lecture and computer laboratory.

56:160:575,576 Special Topics in Chemistry (Variable) Subject matter varies according to the interest of the instructor and is drawn from areas of current interest.

56:160:580 Forensic Chemistry (3) This course introduces students to the intersection of chemistry, its principles and techniques, with the criminal justice system.  Topics such as drug detection, arson investigation, and trace evidence will be addressed.

56:160:582 Forensic Chemistry Lab (1) This lab will instruct students in the practical techniques used in a Forensic Chemistry Unit.  Students will learn presumptive and confirmatory testing methods. Pre- or Co-requisite: 56:160:580

56:160:584 Forensic Toxicology (3) This course addresses the detection, identification and quantitation of foreign chemicals (toxins) in the body. Students will utilize their theoretical knowledge of pharmacology to develop their knowledge of the types of toxic substances and matrices encountered and the procedures by which these are tested in the laboratory. 

56:160:586 Forensic Toxicology Laboratory (1) State of the art methods related to the detection and interpretation of forensically relevant toxicological substances. Pre- or Co-requisite: 56:160:584

56:160:601,602 Seminar in Chemistry (1,1) A variety of topics of current interest regularly presented and discussed by students, faculty, and invited experts. Full-time graduate students must give an oral presentation annually. First-year, full-time students (Plan A: Thesis) must present their proposed research project to the graduate faculty before spring break. Students who anticipate degree completion (Plan A: Thesis or Plan B: Nonthesis) must present by mid-April for a May-dated degree (early September for an October-dated degree).

56:160:611 Fundamentals of Pharmacology and Pharmacokinetics (3) This course provides a theoretical foundation of pharmacology including pharmacokinetics and pharmacodynamics. Topics include absorption, distribution, pharmacological effects, metabolism and excretion of foreign chemicals with an emphasis on drugs of abuse. 

56:160:619,620 Independent Studies in Chemistry (Variable) Designed for students conducting original projects in chemistry either as part of the thesis research or for the nonthesis option. The project is designed and conducted in consultation with a sponsor from, or designated by, the graduate faculty. Nonthesis students complete 2 credits culminating in a written term paper and oral presentation before the graduate faculty. Generally thesis students complete at least 4 credits culminating in a written thesis and seminar presentation.

56:160:701,702 Research in Chemistry (Variable) Open only to students working on research for the thesis. Prerequisite: Permission of thesis adviser.

56:160:800 Matriculation Continued (0) Continuous registration may be accomplished by enrolling for at least 3 credits in standard courses, including research courses, or by enrolling in this course for 0 credits. Students actively engaged in study toward their degree who are using university facilities and faculty time are expected to enroll for the appropriate credits.

56:115:511,512 Biochemistry I, II (3,3) Study of the structure and function of proteins and enzymes. Analysis of the chemistry of carbohydrates, lipids, and nucleic acids. Detailed survey of metabolic pathways, with an emphasis on regulation.

56:115:522 Protein Structure and Function (3) Basic structural principles of polypeptides, mechanisms of enzyme catalysis, biophysical techniques used in the determination of protein structure, protein folding, protein-protein interactions, protein engineering.

56:115:524 Natural Product Chemistry (3) Survey of carbohydrates, amino acids, peptides, biopolymers, heteroaromatics, terpenes, steroids, fatty acids, and alkaloids.

56:115:525 Pharmaceutical Chemistry (3) This class will focus on the drug likeness of chemicals. Absorption, Distribution, Metabolism and Exclusion (ADME) and toxicity are those critical reasons to determine a compound to be an efficacious drug-like compound or not. The application of ADME/Tox research has been expanded from optimizing in vivo pharmacokinetics and safety to designing proper bioassay protocols. This class is to teach the students who will have the potentials to be engaged in the research and design process of new drugs.

56:115:527 Bionanotechnology: Discovery, Assembly, Function and Application (3) Bionanotechnology is an emerging field that applies the fundamentals of nanotechnology to solving relevant biological and chemical problems and refining new methods and tools for medicine and energy. Nanotechnology refers to the revolutionary technology that manipulates matter with matter with at least one dimension sized from 1 to 100 nanometers. Molecular structures exhibit unique properties at this scale where the quantum phenomenon starts to play an important role as compared to bulk materials. Bionanotechnology describes the overlapping multidisciplinary activities where photonics, chemistry, biology, biophysics, nano-medicine, and engineering converge.

56:115:530 Forensic & Analytical Molecular Biology (3) This course provides a survey of the theories, quantitative analysis methods and molecular bio-techniques commonly employed in forensic operations. Topics include genome structure, nucleic acid extraction, real-time PCR, digital PCR, end-point PCR, recombinant DNA techniques, interrelationship of DNA-RNA-protein synthesis, capillary electrophoresis, Sanger sequencing, massive parallel sequencing, dynamic modeling and probabilistic genotyping for inference.

56:115:531 Forensic DNA Laboratory (1) At the completion of this course students will have an understanding of basic protocols, bio-analytical techniques and procedures commonly applied in forensic DNA testing. They will be exposed to state-of-the-art forensic DNA interpretation methods based on probabilistic genotyping and will gain experience with common DNA extraction procedures, the polymerase chain reaction, the absolute quantification with real-time PCR, DNA fragment analysis using capillary electrophoresis and quality control measures implemented in the human identification laboratory.

56:115:571 Forensic Serology (3) This course addresses the theory and practice of forensic serology.  Students will learn the presumptive and confirmatory testing methods used to determine the type and source of biological stains along with new technologies under development. Advanced techniques such as qPCR and mass spectrometry may also be explored.

56:115:573 Forensic Serology Laboratory (1) This lab section provides practical training in forensic serological techniques. Exposure to techniques including lateral flow immunochromatography and microscopy for purposes of fluid-type categorization will be explored. Pre- or Co-requisite: 56:115:571

56:115:575,576 Special Topics in Biochemistry (Variable) Subject matter varies according to the expertise of the instructor and is drawn from areas of current biochemical interest.

56:115:619,620 Independent Studies in Biochemistry (Variable) Designed for students conducting original projects in chemistry in lieu of a research thesis. The project is designed and conducted in consultation with a sponsor from, or designated by, the graduate faculty.

56:115:701,702 Research in Biochemistry (Variable) Open only to students working on research for their thesis. Prerequisite: Permission of thesis adviser.